| CAS
NO. |
145224-94-8 |
|
| EINECS
NO. |
|
| FORMULA |
C6H13NO4S·H2O |
| MOL
WT. |
213.25 |
| H.S.
CODE |
|
| SMILES |
|
| TOXICITY |
|
| SYNONYMS |
MES
monohydrate;
Morpholineethanesulfonic acid monohydrate; |
| 2-(4-Morpholinyl)ethanesulfonic acid
monohydrate; 2-(N-Morpholino)ethanesulfonic acid monohydrate;
2-Morpholinoethanesulfonic acid monohydrate; 4-Morpholinethanesulfonic acid
monohydrate; Morpholino-N-ethylsulfonate monohydrate;
Morpholinoethanesulfonic acid monohydrate; |
|
CLASSIFICATION
|
|
|
PHYSICAL
AND CHEMICAL PROPERTIES
|
| PHYSICAL
STATE |
white
crystalline powder |
| MELTING
POINT |
>300 C
(Decomposes) |
| BOILING
POINT |
|
| SPECIFIC
GRAVITY |
|
| SOLUBILITY
IN WATER |
Soluble |
| AUTOIGNITION
|
|
| pH |
|
| VAPOR
DENSITY |
|
| NFPA
RATINGS |
Health:
1; Flammability: 0; Reactivity: 0 |
|
REFRACTIVE
INDEX
|
|
| FLASH
POINT |
|
| STABILITY |
Stable
under ordinary conditions. Hygroscopic. |
|
GENERAL
DESCRIPTION & APPLICATIONS
|
|
MES is one of a number of so-called "Good" buffers
developed for biological applications, with the criteria: midrange
pKa, maximum water solubility and minimum solubility in all other
solvents, minimal salt effects, minimal change in pK with temperature,
chemically and enzymatically stable, minimal absorption in visible
or UV spectral range and reasonably easily synthesized. MES is not
recommended for buffering at pH 7.4; other buffers should be considered
(http://www.sigmaaldrich.com)
List
of Good's buffers
|
| SALES
SPECIFICATION |
|
APPEARANCE
|
white
crystalline powder |
| ASSAY |
99.0%
min
|
|
pKa
|
6.1
(25C), 6.15 (20C)
|
|
WATER
|
10.0%
max
|
|
pH
|
2.5 - 4.0 (0.5 M in H2O, 25 C)
|
|
USEFUL
pH RANGE
|
5.5 - 6.7 |
| TRANSPORTATION |
| PACKING |
1kgs,
25kgs
in fiber drum |
| HAZARD
CLASS |
Not
regulated |
| UN
NO. |
|
| OTHER
INFORMATION |
| Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety
Phrases: 26-36 |